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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1D
All Species:
34.55
Human Site:
T250
Identified Species:
58.46
UniProt:
P48730
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48730
NP_001884.2
415
47330
T250
G
Y
P
S
E
F
A
T
Y
L
N
F
C
R
S
Chimpanzee
Pan troglodytes
XP_001167759
427
49046
T250
G
Y
P
S
E
F
A
T
Y
L
N
F
C
R
S
Rhesus Macaque
Macaca mulatta
XP_001113761
317
36681
D158
G
L
A
K
K
Y
R
D
A
R
T
H
Q
H
I
Dog
Lupus familis
XP_533137
393
45057
T234
S
Y
P
S
E
F
A
T
Y
L
N
F
C
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC28
415
47298
T250
G
Y
P
S
E
F
A
T
Y
L
N
F
C
R
S
Rat
Rattus norvegicus
P97633
325
37477
D166
G
L
A
K
K
Y
R
D
N
R
T
R
Q
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLL1
416
47453
T250
G
Y
P
S
E
F
S
T
Y
L
N
F
C
R
S
Frog
Xenopus laevis
Q5BP74
415
47421
T250
G
Y
P
S
E
F
A
T
Y
L
N
F
C
R
S
Zebra Danio
Brachydanio rerio
Q6P3K7
409
46813
T250
G
Y
P
S
E
F
A
T
Y
L
N
F
C
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76324
440
47939
N250
G
F
P
S
E
F
V
N
Y
L
N
F
C
R
Q
Honey Bee
Apis mellifera
XP_395574
413
47530
Q250
G
Y
P
V
E
F
V
Q
Y
L
R
Y
C
R
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779963
435
49455
T250
G
Y
S
P
E
F
A
T
Y
L
N
H
T
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
S250
G
Y
P
S
E
F
A
S
Y
F
H
Y
C
R
S
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
E250
G
L
P
L
E
F
Q
E
Y
M
A
Y
C
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
76.1
90.3
N.A.
99.7
56.8
N.A.
N.A.
83.8
96.6
91
N.A.
62.5
66.7
N.A.
71
Protein Similarity:
100
95.3
76.3
91.5
N.A.
100
65.3
N.A.
N.A.
88.9
97.8
94.6
N.A.
72
77.1
N.A.
78.8
P-Site Identity:
100
100
6.6
93.3
N.A.
100
6.6
N.A.
N.A.
93.3
100
100
N.A.
73.3
60
N.A.
66.6
P-Site Similarity:
100
100
20
93.3
N.A.
100
20
N.A.
N.A.
100
100
100
N.A.
80
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
47.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.5
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
58
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
79
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
86
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
86
0
0
0
8
0
58
0
0
0
% F
% Gly:
93
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
15
0
15
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
0
0
0
15
15
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
22
0
8
0
0
0
0
0
72
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
65
0
0
0
15
% N
% Pro:
0
0
79
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
0
0
0
15
0
8
% Q
% Arg:
0
0
0
0
0
0
15
0
0
15
8
8
0
79
0
% R
% Ser:
8
0
8
65
0
0
8
8
0
0
0
0
0
0
58
% S
% Thr:
0
0
0
0
0
0
0
58
0
0
15
0
8
0
0
% T
% Val:
0
0
0
8
0
0
15
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
72
0
0
0
15
0
0
86
0
0
22
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _